A novel lamprey antibody sequence to multimerize and increase the immunogenicity of recombinant viral and bacterial vaccine antigens

A novel lamprey antibody sequence to multimerize and increase the immunogenicity of recombinant viral and bacterial vaccine antigens

emagglutinin, the main floor protein of influenza viruses, was recombinantly expressed in eukaryotic cells as a monomer as a substitute of its native trimer, and was solely immunogenic when administered with an adjuvant [Pion et al. 2014]. With the intention to multimerize this antigen to extend its immunogenicity, a cysteine-rich peptide sequence discovered on the […]

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