A novel lamprey antibody sequence to multimerize and increase the immunogenicity of recombinant viral and bacterial vaccine antigens

A novel lamprey antibody sequence to multimerize and increase the immunogenicity of recombinant viral and bacterial vaccine antigens

emagglutinin, the main floor protein of influenza viruses, was recombinantly expressed in eukaryotic cells as a monomer as a substitute of its native trimer, and was solely immunogenic when administered with an adjuvant [Pion et al. 2014]. With the intention to multimerize this antigen to extend its immunogenicity, a cysteine-rich peptide sequence discovered on the […]

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[Ocular manifestations of viral diseases]

[Ocular manifestations of viral diseases]

Viral infections may involve all ocular tissues and may have short and long-term sight-threatening consequences. Among them, ocular infections caused by herpesviruses are the most frequent. HSV-1 keratitis and kerato-uveitis affect approximately are the leading cause of infectious blindness in the Western world, mainly because of corneal opacification caused by recurrences. For this reason, they […]

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Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution

Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution

Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state) after 39 years of no reported case in Nigeria, and the export of travelers’ monkeypox (MPX) from Nigeria to other parts of the world, in 2018 and 2019, respectively, […]

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